Thymus and Lymph Nodes Following Adrenalectomy and Maintenance with NaCl in the Rat.

The thymus gland of adrenalectomized male rats maintained for 45 days on sodium chloride does not undergo the involution characterizing the gland in normal untreated animals or those treated with sodium chloride. Sodium chloride as employed appears to exert no consistent effect per se on the thymus or lymphoid tissues of the unoperated control. 2. The systemic lymph nodes of adrenalectomized animals maintained on sodium chloride were heavier than those of normal untreated animals or normal animals given sodium chloride. It is notable that the mesenteric lymph nodes do not undergo a comparable gravimetric increase.