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July 1, 1992Proceedings of the National Academy of Sciences

Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.

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Authors

EMEugene MechetnerExpedia Group (United States)IRIgor B. RoninsonUniversity of South Carolina

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Mechetner et al. (1992) studied this question.

synapsesocial.com/papers/6a94d55d53e09118be7c3e89https://doi.org/10.1073/pnas.89.13.5824
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Also Consider

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  1. 1Reversal of Drug Resistance in a Human Colon Cancer Xenograft Expressing MDR1 Complementary DNA by In Vivo Administration of MRK-16 Monoclonal Antibody1991 · 82 citations
  2. 2Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection.1991 · 76 citations
  3. 3Monoclonal Anti‐P‐glycoprotein Antibody‐dependent Killing of Multidrug‐resistant Tumor Cells by Human Mononuclear Cells1990 · 32 citations
  4. 4Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase.1988 · 335 citations