Key result
In vivo fluorescence microscopy with epi-illumination demonstrated that the hepatic microcirculation and microhemodynamics of Syrian golden hamsters are similar to those of rats.
Population
Syrian golden hamsters and rats
Comparison
Intravital fluorescence microscopy and… vs Comparison between hamsters and rats
Design
Preclinical
Authors
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Supports hamster liver as alternative model for microcirculation studies; leaves open human translation.
In vivo microscopy of the hamster liver using epi-illumination represents a favorable model for studying cellular phenomena within the hepatic microcirculation.
Menger et al. (2008) studied Hepatic microcirculation (animal model). Intravital fluorescence microscopy and epi-illumination vs. Rats was evaluated on Morphology and microhemodynamics of the hepatic microcirculatory system. In vivo fluorescence microscopy with epi-illumination demonstrated that the hepatic microcirculation and microhemodynamics of Syrian golden hamsters are similar to those of rats.