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January 1, 1976Thrombosis and Haemostasis

Role of Surface Glycoproteins in Human Platelet Function

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Population

Human platelets, including observations from patients with Glanzmann's thrombasthenia and Bernard Soulier…

Design

Review

Authors

ANAlan T. NurdenUniversité Paris-SudJCJ CaenUniversité Claude Bernard Lyon 1

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Implication

Supports diagnostic evaluation of glycoprotein-related bleeding disorders; leaves open therapeutic implications for thrombosis prevention.

Structured PICO

P
Population
Human platelets, including observations from patients with Glanzmann's thrombasthenia and Bernard Soulier syndrome

Surface glycoproteins on human platelets are essential for platelet aggregation and adhesion, with specific deficiencies linked to bleeding disorders like Glanzmann's thrombasthenia and Bernard Soulier syndrome.

Cite This Study

Nurden et al. (1976) studied this question.

synapsesocial.com/papers/6a94d7ffc05e7b5813b2c199https://doi.org/10.1055/s-0038-1647939
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Role of the Platelet Glycoprotein IIb / IIIa in Thrombosis and Haemostasis2004 · 129 citations
  2. 2Platelets and Hemostasis: The Role of Glycoprotein IIb/IIIa in Platelet Aggregation1997 · 2 citations
  3. 3Absence of the 145,000 Molecular Weight, Soluble Platelet Membrane Glycoprotein - Lack of Platelet Agglutination1979 · 11 citations
  4. 4Molecular Analyses of the Platelet Glycoprotein Ib-IX-V Receptor1998 · 55 citations
  5. 5Polymorphisms of Human Platelet Membrane Glycoproteins: Structure and Clinical Significance1995 · 98 citations