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The in vitro comparison of two SSPE measles virus isolates and conventional measles virus demonstrated antigenic identity between these viruses. However, neutralization tests showed an avidity of the SSPE patient's neutralizing antibody towards the wild measles virus rather than to the virus isolated from diseased brain. The cytopathology and plaque formation of these measles virus strains revealed greater resemblance between the SSPE measles and the vaccine strain of the virus than between SSPE measles and wild virus. Differences were found in the growth characteristics of the two SSPE virus isolates as measured by tissue culture assays.
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Horta-Barbosa et al. (1970) studied this question.
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