Key result
The XIAP IRES provokes the production of monocistronic mRNA encompassing the 3' cistron in the betagal/CAT bicistronic reporter plasmid through cryptic promoter activity.
Authors
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Questions XIAP IRES interpretations in reporter assays; leaves open whether native IRES activity exists.
Saffran et al. (2009) studied this question. XIAP IRES was evaluated on Production of monocistronic mRNA. The XIAP IRES provokes the production of monocistronic mRNA encompassing the 3' cistron in the betagal/CAT bicistronic reporter plasmid through cryptic promoter activity.
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