Incidence of Endophthalmitis After Intra-Operative Moxifloxacin Injection in the Capsular Bag, Behind the Intra Ocular Lens, in Phacoemulsification. A Retrospective Study

Purpose: to evaluate the efficacy and safety of intracapsular moxifloxacin injection at the endof phacoemulsification as a prophylactic measure against early and late endophthalmitis.Setting: private eye center, eye Care, Cairo, Egypt. Methods: This is a retrospective clinicalregistry-based study. Data was collected from patients who had phacoemulsification withinthe capsular bag injection of moxifloxacin at the end of surgery. 0.2 ml of moxifloxacin 0.5%ophthalmic solution was injected into the bag by placing the tip of the cannula under thecapsulorhexis edge and directing the drug behind the IOL. Results: Data were collected fromEMR for 10919 eyes, that underwent phacoemulsification and in the bag moxifloxacin injectionbetween January 2015 and August 2022, 4 cases of early endophthalmitis were reported with anincidence of 0.03%, no cases of late-endophthalmitis, and no cases of toxicity. Conclusion:Intracapsular moxifloxacin injection at the end of phacoemulsification is a safe effectiveprophylactic measure against endophthalmitis.