Analysis of The Effect of Syringe Barrel Volume on Mechanical Failure During Injection

Background: Syringes are critical medical devices whose mechanical integrity is essential to ensure safety during injections. The cylinder volume can influence their mechanical performance. Objective: This study investigates how cylinder volume affects the mechanical integrity of syringes by analyzing von Mises stress, buckling risk, and overall safety during injection. Materials and Methods: Autodesk Inventor 2021 and Ansys 2019 R2 were used to analyze syringes with volumes of 1 ml, 3 ml, 5 ml, and 10 ml. Von Mises stress and buckling susceptibility were evaluated during simulated injections. Results: Smaller syringes showed higher stress levels: 14.030 MPa for the 1 ml syringe, 10.532 MPa for the 3 ml, and 7.0150 MPa for the 5 ml and 10 ml. The 5 ml syringe was the most susceptible to buckling, with a critical pressure of -0.1757 MPa. Despite this, all designs are safe under normal operating conditions. Conclusions: Cylinder volume affects mechanical performance, but with proper design, even smaller syringes can remain safe, enhancing the reliability of medical treatments.