Key result
Myosin VI is the first motor protein shown to associate with clathrin-coated pits and modulate clathrin-mediated endocytosis by moving towards the minus end of actin filaments.
Population
Polarised cells / clathrin mediated endocytosis models
Design
Review
Authors
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Identifies myosin VI in endocytosis; leaves open its relevance to cardiovascular cell trafficking.
Myosin VI plays a key role in modulating clathrin-mediated endocytosis by moving towards the minus end of actin filaments.
Buß et al. (2001) conducted a review in Clathrin mediated endocytosis. Myosin VI was evaluated. Myosin VI is the first motor protein shown to associate with clathrin-coated pits and modulate clathrin-mediated endocytosis by moving towards the minus end of actin filaments.
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