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June 6, 2022Open Access

Impact of acute mental stress on ankle blood pressure in young healthy men: a pilot study

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Why the study?

Does acute mental stress increase ankle blood pressure in young healthy men?

Population

56 young, healthy men, non-smokers, taking no medications. Divided into mental stress and control groups.

Comparison

5-minute acute mental stress task consisting of… vs 5-minute control task consisting of slowly…

Design

Other

Follow-up

30 minutes post-task

Key result

Acute mental stress significantly increased ankle systolic blood pressure at 30 minutes post-task compared to a control task (interaction p<0.001) in young healthy men.

Authors

DKDaisuke KumeMNMasato NishiwakiNHNorio Hotta

Discussion

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Member takes

Overview

May affect ankle BP interpretation after acute stress; hypothesis-generating for vascular reactivity studies.

Study Design

Type

RCT (n=56)

Multicenter

No

Structured PICO

Does acute mental stress increase ankle blood pressure in young healthy men?

P
Population
56 young, healthy men aged 19-24 years, free of medication and smoking, who underwent a 5-minute mental stress task with 30 minutes of follow-up.
I
Intervention
5-minute acute mental stress (MS) task consisting of mental arithmetic (serially subtracting 13 from a 3-digit number) with harassment and metronome noise.
C
Comparator
5-minute control (CON) task consisting of slowly counting upward from 1 without harassment or noise.
O
Outcome
Systolic and diastolic blood pressures (SBP and DBP) of both the brachial and posterior tibial (ankle) arteries measured at baseline, 5 minutes, and 30 minutes after the task.surrogate

Main Result

Absolute Event Rate: 137% vs 132%

p-value: p=<0.001

Acute mental stress induces a sustained elevation in both brachial and ankle blood pressure in young healthy men, suggesting a systemic pressor response.

Limitations

  • Only young, healthy men were included, limiting generalizability to women, older individuals, and hypertensive patients.
  • Ankle blood pressure measurements were not taken during the acute mental stress task.
  • Only young, healthy men were included
  • Ankle BP measurements were not taken during acute MS

Cite This Study

Kume et al. (2022) conducted an RCT in Healthy (n=56). Acute mental stress (mental arithmetic task) vs. Control task (counting upward) was evaluated on Ankle systolic blood pressure at 30 minutes post-task (p=<0.001). Acute mental stress significantly increased ankle systolic blood pressure at 30 minutes post-task compared to a control task (interaction p<0.001) in young healthy men.

synapsesocial.com/papers/6a94ec2a0af64aa4440b21c9https://doi.org/10.21203/rs.3.rs-1574443/v1
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