Population
Isolated segments of canine small-caliber arteries
Comparison
Epinephrine and electrical current stimulation vs Normal state versus potassium-depolarized state
Design
Preclinical
Authors
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Epinephrine contracts arteries independently of depolarization; leaves open translation to human vascular physiology.
Epinephrine induces contractile responses in arterial smooth muscle independent of potassium depolarization, whereas electrical stimulation is impaired.
William H. Waugh (1962) studied this question.
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