Recently, in the clinical practice of treating hepatobiliary diseases, significant progress has been made in understanding the molecular basis of bile formation and cholestasis pathophysiology. This article briefly summarizes the modern concepts of bile formation and cholestasis. The goals of drug therapy for cholestasis have been determined, which help to understand existing methods of treating cholestasis and contribute to the development of new agents for cholestatic liver diseases.
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Polunina Te (2022) studied this question.
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