Why the study?
Does increased intracranial pressure affect basilar artery flow velocity and cortical microcirculation in a rabbit model?
Population
New Zealand White rabbits under alpha-chloralose anesthesia and artificial respiration
Design
Preclinical
Authors
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TCD indices may flag critical microcirculatory impairment below 35 mm Hg CPP in rabbits; leaves open human validation before clinical use.
Does increased intracranial pressure affect basilar artery flow velocity and cortical microcirculation in a rabbit model?
Transcranial Doppler indices can detect critical reductions in microcirculatory blood flow when cerebral perfusion pressure drops below 35 mm Hg in a rabbit model of intracranial hypertension.
Ungersböck et al. (1995) studied this question.
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