Key result
Obesity was significantly associated with uncontrolled hypertension (AOR 2.90), along with physical activity and low HDL-C, in a cohort where 56.83% of treated patients had uncontrolled blood pressure.
Why the study?
Achieving blood pressure targets remains a challenge and the actual burden of uncontrolled hypertension is poorly understood, particularly in developing countries.
What is the prevalence and what are the determinants of uncontrolled hypertension among adult residents of Mkhondo municipality on antihypertensive treatment?
Cross-Sectional (n=329)
Yes
What is the prevalence and what are the determinants of uncontrolled hypertension among adult residents of Mkhondo municipality on antihypertensive treatment?
Odds Ratio: 2.9 (95% CI 1.66–5.05)
Absolute Event Rate: 63.29% vs 45.9%
p-value: p=<0.001
In a rural South African cohort on antihypertensive therapy, over half of the patients had uncontrolled hypertension, which was independently associated with obesity, physical inactivity, and low HDL-C.
Uncontrolled hypertension prevalence in rural primary care signals need for targeted strategies; cross-sectional associations leave open causal pathways for trials.
Background: Achieving the blood pressure treatment target in individuals with hypertension is a serious global health challenge. Furthermore, the actual burden of uncontrolled hypertension is poorly understood especially in the developing countries. Therefore, this study comprehensively examined the rate and factors associated with uncontrolled hypertension in individuals receiving care at the primary healthcare facilities in the rural areas of Mkhondo Municipality in the Mpumalanga Province, South Africa.Methods: In this cross-sectional study, individuals attending care for hypertension were recruited from January 2019 to June 2019 at three primary healthcare centres, namely, Piet Retief hospital, Mkhondo town clinic and Thandukukhanya community health centre. Uncontrolled hypertension was defined as systolic blood pressure ≥ 140mmHg and diastolic blood pressure ≥ 90mmHg in accordance with the South African Hypertension Society guideline (2014). Multivariate logistic regression (Forward LR method) analysis was used to identify the significant determinants of uncontrolled hypertension.Results: The majority of the participants were; 55 years old and above (69.0%), Zulus (81.2%), non-smokers (84.19%) and had been diagnosed with hypertension for more than a year prior to the study (72.64%). The overall prevalence of uncontrolled hypertension was 56.83% (n=187) with no significant difference between sexes, 57.38% males versus 56.88% females, respectively. In the multivariate logistic regression model analysis after adjusting for confounding variables, obesity (AOR=2.90; 95% CI 1.66-5.05), physical activity (AOR=4.79; 95% CI 2.15-10.65) and HDL-C (AOR=5.66; 95% CI 3.33-9.60) were the significant and independent determinants of uncontrolled hypertension in the cohort.ConclusionThe high rate of uncontrolled hypertension in the study setting, can be largely attributed to obesity, physical activity and dyslipidaemia. Treatment will require the collaborative efforts of individuals, clinicians and health authorities. All these determinants should be addressed decisively so as to achieve the treatment blood pressure targets in the study population.
No takes yet. Share an insight, caveat, or question.
Masilela et al. (2020) conducted a cross-sectional in Hypertension (n=329). Obesity vs. Non-obese was evaluated on Uncontrolled hypertension (SBP ≥ 140 mmHg or DBP ≥ 90 mmHg) (AOR 2.90, 95% CI 1.66-5.05, p=<0.001). Obesity was significantly associated with uncontrolled hypertension (AOR 2.90), along with physical activity and low HDL-C, in a cohort where 56.83% of treated patients had uncontrolled blood pressure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: