Key result
Permanent pacemaker implantation after cardiac surgery was not associated with long-term mortality after adjustment for risk factors and surgical procedure (HR 1.3; 95% CI 0.9-1.9; P=0.17).
Why the study?
Does permanent pacemaker implantation after cardiac surgery affect long-term mortality in patients undergoing cardiac surgery?
Cohort (n=6,268)
No
Does permanent pacemaker implantation after cardiac surgery affect long-term mortality in patients undergoing cardiac surgery?
Hazard Ratio: 1.3 (95% CI 0.9–1.9)
Absolute Event Rate: 45% vs 36%
p-value: p=0.17
Permanent pacemaker implantation after cardiac surgery is not associated with increased long-term mortality after adjusting for confounders, and the majority of patients are not pacemaker-dependent in the long term.
No takes yet. Share an insight, caveat, or question.
May reassure on mortality risk with indicated post-surgical pacing after adjustment; leaves open causal effects and dependency for prospective trials.
Raza et al. (2011) conducted a cohort in cardiac surgery (n=6,268). Permanent pacemaker (PPM) implantation vs. No permanent pacemaker was evaluated on long-term mortality (HR 1.3, 95% CI 0.9-1.9, p=0.17). Permanent pacemaker implantation after cardiac surgery was not associated with long-term mortality after adjustment for risk factors and surgical procedure (HR 1.3; 95% CI 0.9-1.9; P=0.17).
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