Nano-hydroxyapatite and its contemporary applications

Combination of nano‑sized hydroxyapatite (nHA) with restorative materials like glass ionomer cement and composite resins has been reported recently in 2011. The documented effects of these nano‑sized particles on the chemistry of these materials include increased biocompatibility and mechanical strength. nHA has been utilized for various applications like pulp capping agent, root canal sealer, filler for bleaching agents and toothpastes, osseo‑conductive bone graft etc., A nHA has been obtained using natural bovine bone, carbon template technique, hydroxyapatite‑chitosan template technique, wet precipitation technique, plasma spraying technique etc. This paper presents a review of the various aspects of nHA and summarizes the methods of fabrications and potential clinical applications of the same.