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May 1, 1999Endocrinology

Liarozole Acts Synergistically with 1α,25-Dihydroxyvitamin D3to Inhibit Growth of DU 145 Human Prostate Cancer Cells by Blocking 24-Hydroxylase Activity1

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Authors

LLLan H. LyUniversity of Tennessee Health Science CenterXZXiao-Yan ZhaoBayer (United States)LHLeah HollowayGroup for the Analysis of Development

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Ly et al. (1999) studied this question.

synapsesocial.com/papers/6a95009bc05e7b5813b2cd75https://doi.org/10.1210/endo.140.5.6698
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hormonal responses to 1,25‐dihydroxyvitamin D3 in cultured mouse osteoblast‐like cells—modulation by changes in receptor level1986 · 66 citations
  2. 2Ketoconazole and Other Imidazole Derivatives as Inhibitors of Steroidogenesis1986 · 219 citations
  3. 3The Effects of 1,25-Dihydroxyvitamin D3and Dexamethasone on Rat Osteoblast-Like Primary Cell Cultures: Receptor Occupancy and Functional Expression Patterns for Three Different Bioresponses*1986 · 109 citations
  4. 4Effect of Retinoic Acid on the Proliferation and Secretory Activity of Androgen-Responsive Prostatic Carcinoma Cells1993 · 74 citations
  5. 5Antiproliferative Effect of 1 ,25-Dihydroxyvitamin D3 in Human Prostate Cancer Cell Line LNCaP Involves Reduction of Cyclin-Dependent Kinase 2 Activity and Persistent G1 Accumulation1998 · 46 citations