Population
Saccharomyces cerevisiae (yeast) model for L-A double-stranded RNA virus
Design
Preclinical
Authors
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ORF1 may target the SKI antiviral system in yeast; leaves open its role in natural dsRNA virus defense.
Expression of the major coat protein (ORF1) of the yeast L-A double-stranded RNA virus acts as a ski- phenocopy, suggesting it may be a target of the SKI antiviral system.
Wickner et al. (1991) studied this question.
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