Key result
A 39-year-old male with poliomyelitis developed a rare, delayed-onset malignant hyperthermia crisis 4 hours after surgery involving succinylcholine, successfully treated with dantrolene.
Case Report (n=1)
No
This case report highlights that malignant hyperthermia can present with delayed onset (4 hours postoperatively) in patients with neuromuscular disorders such as poliomyelitis.
May indicate delayed MH risk in poliomyelitis; hypothesis-generating for perioperative vigilance in neuromuscular disorders.
Malignant hyperthermia (MH) is a rare hypermetabolic response to halogenated anesthetic gases or succinylcholine. We presented a case of malignant hyperthermia in a 39-year-old male with a past medical history significant for poliomyelitis, who had been exposed to anesthetic agents multiple times in the past. The patient presented with MH crisis about 4 h after surgery, with pre operative exposure to succinylcholine. Seventy percent of MH cases are familial ones and sporadic cases are rare. This case report creates awareness of the diagnosis of MH in patients without family history of the disorder and with delayed symptom onset. Studies are lacking on the pathophysiology of MH in patients with neuromuscular disorders since these patients might have atypical presentation. J Med Cases. 2018;9(7):236-237 doi: https://doi.org/10.14740/jmc3083w
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Syed et al. (2018) conducted a case report in Malignant hyperthermia (n=1). Succinylcholine was evaluated on Malignant hyperthermia crisis. A 39-year-old male with poliomyelitis developed a rare, delayed-onset malignant hyperthermia crisis 4 hours after surgery involving succinylcholine, successfully treated with dantrolene.
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