What question did this study set out to answer?

Determine whether surgically attaching intestinal loops to the myocardium can establish functional vascular anastomoses to revascularize cardiac tissue.

November 1, 1954Circulation Research

Use of Intestinal Loops for Revascularization of the Heart

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Population

Preclinical model (unspecified animal)

Design

Preclinical

Authors

IBIvan D. BaronofskyMarquette University JSJoseph L. SprafkaUniversity of Minnesota JNJohn F. NobleFundación Juan March

Discussion

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Implication

Experimental intestinal-myocardial vascular connections suggest a revascularization strategy; hypothesis-generating and should not alter clinical practice.

Key Points

Determine whether surgically attaching intestinal loops to the myocardium can establish functional vascular anastomoses to revascularize cardiac tissue.
Transposed intestinal loops through the diaphragm and surgically affixed them directly to the myocardium.
Assessed collateral vascular connections and vessel patency via mesenteric injections of thick barium sulfate suspensions and India ink.
New vascular channels developed between the intestinal loop and cardiac tissue, demonstrating calibers sufficient to transmit thick suspensions of barium sulfate.
Mesenteric injection of India ink resulted in widespread dye distribution across all outer cardiac surfaces and deep within the myocardium.

Structured PICO

Population

Preclinical model (unspecified animal)

Intervention

Intestinal loops brought up through the diaphragm and attached to the myocardium

Outcome

Formation of connections between the vascular supplies of the heart and intestinesurrogate

Attaching intestinal loops to the myocardium establishes vascular connections capable of transmitting fluids, demonstrating a potential experimental mechanism for myocardial revascularization.

Cite This Study

Baronofsky et al. (1954) studied this question.

synapsesocial.com/papers/6a950480948c2c98a4f57e8d https://doi.org/10.1161/01.res.2.6.506

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Implication

Experimental intestinal-myocardial vascular connections suggest a revascularization strategy; hypothesis-generating and should not alter clinical practice.

Use of Intestinal Loops for Revascularization of the Heart

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Use of Intestinal Loops for Revascularization of the Heart

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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