Key result
Total aortic arch replacement with frozen elephant trunk for acute and chronic aortic dissections demonstrated pooled in-hospital mortality rates of 8.4% and 7.5%, respectively.
Why the study?
Total aortic arch replacement with frozen elephant trunk is increasingly used for aortic pathologies, motivating a focus on techniques and outcomes for DeBakey I aortic dissections.
Does total aortic arch replacement with frozen elephant trunk improve outcomes in patients with DeBakey I aortic dissections?
Does total aortic arch replacement with frozen elephant trunk improve outcomes in patients with DeBakey I aortic dissections?
Total aortic arch replacement with frozen elephant trunk is a viable alternative to conventional open surgical repair for DeBakey I aortic dissections, demonstrating acceptable mortality and high rates of false lumen thrombosis.
May inform FET technique selection in dissection; extends pooled literature but leaves open need for RCTs.
Total aortic arch replacement (TAR) with frozen elephant trunk (FET) technique (FET) has been increasingly used to treat a variety of aortic pathologies over the past two decades. Because FET can effectively treat the diseased arch and cover the proximal entry tear in the distal arch, it is a valuable option in the treatment of DeBakey I aortic dissections. This report focuses on the techniques and outcomes of TAR with FET for acute/chronic aortic dissection. A review of pooled literature including 27 observational studies showed in-hospital mortality, permanent stroke, and spinal cord injury rates of 8.4%, 5.9% and 2.6% for acute aortic dissections, and 7.5%, 4.0% and 4.6% for chronic aortic dissections, respectively. In most of the studies, complete false lumen thrombosis rate was achieved in 80% of patients at the level of FET for acute and chronic aortic dissections. Mid-term outcomes are equally promising. For chronic aortic dissections, positive remodeling of the non-stented distal aortic segments is less frequent leading to secondary reinterventions within 3 to 5 years. However, most studies have not applied distal abdominal extensions of the repair using fenestrated and branched endografts. In the current endovascular era, TAR + FET should be considered as an alternative to conventional open surgical repair in centers of excellence.
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Kawajiri et al. (2020) conducted a review in DeBakey I aortic dissections (acute and chronic). Total aortic arch replacement (TAR) with frozen elephant trunk (FET) was evaluated on In-hospital mortality, permanent stroke, and spinal cord injury. Total aortic arch replacement with frozen elephant trunk for acute and chronic aortic dissections demonstrated pooled in-hospital mortality rates of 8.4% and 7.5%, respectively.
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