Key result
A frozen elephant trunk operation with the E-vita hybrid prosthesis resulted in 100% survival and complete closure of the false lumen in 10 patients with acute Type A dissection.
Why the study?
Does the frozen elephant trunk operation with a hybrid prosthesis safely close the false lumen in patients with acute Type A dissection?
Observational (n=10)
Does the frozen elephant trunk operation with a hybrid prosthesis safely close the false lumen in patients with acute Type A dissection?
The frozen elephant trunk operation using a hybrid prosthesis is a feasible and safe procedure to close the false lumen during primary repair of acute Type A aortic dissection.
Supports hybrid prosthesis feasibility in acute Type A dissection; leaves open confirmation of safety and efficacy in larger prospective studies.
Following successful repair of Type A dissection, late morbidity and mortality depend on the progression of residual chronic Type B dissection. To avoid the development of late aneurysms of the descending thoracic aorta, a persistent aortic false lumen around the stent-graft can be prevented by remodeling the thoracic aorta. Ten consecutive patients (mean age: 56 years) with acute Type A dissection underwent a "frozen elephant trunk operation" with the E-vita hybrid prosthesis, under deep hypothermic circulatory arrest, between October 2009 and April 2010. The thoracic aorta was restored to its original size. Computed tomography was used to size the aortic diameter. All patients survived and were routinely discharged. Postoperative computed tomography showed no remaining false lumen and no distal organ ischemia in any patient. No new neurological complication was recorded. Two patients suffered postoperative pulmonary arterial embolism; one underwent embolectomy. Restoration of the thoracic aorta is a safe procedure to close the false lumen during the primary operation for acute Type A dissection. However, the diameter of the stent should reflect the overall aortic size, independent of the diameter of the true lumen.
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Hoffman et al. (2011) conducted an observational in Acute Type A dissection (n=10). Frozen elephant trunk operation with E-vita hybrid prosthesis was evaluated on Survival and closure of false lumen. A frozen elephant trunk operation with the E-vita hybrid prosthesis resulted in 100% survival and complete closure of the false lumen in 10 patients with acute Type A dissection.
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