Key result
Fine-needle aspiration cytology of proximal-type epithelioid sarcoma showed large, atypical neoplastic cells with rhabdoid-like morphology, correlating well with histopathology.
Case Report (n=1)
Fine-needle aspiration cytology can accurately diagnose recurrences and metastases of 'proximal-type' epithelioid sarcoma when combined with clinical information and ancillary studies.
May aid FNA diagnosis of proximal-type epithelioid sarcoma recurrences; leaves open need for validation in larger series.
The cytologic and immunocytologic findings in a case of recurrent "proximal-type" epithelioid sarcoma (ES) of the vulva are presented. This is a recently described neoplasm that differs clinically and morphologically from conventional ES. Cytologic smears showed a dissociated population of large, atypical neoplastic cells with bi- and multinucleated cells, abundant cytoplasm, and rhabdoid-like morphology. Due to its different clinical management it must be differentiated from metastatic carcinoma and melanoma. From a practical perspective, its differentiation from other epithelial-like sarcomas is less important. In conclusion the cytopathologic findings of "proximal-type" ES show a good correlation with histopathology, permitting the diagnosis of recurrences and metastases. When accompanied by adequate clinical information and ancillary studies, a specific preoperative recognition seems possible.
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González‐Peramato et al. (2001) conducted a case report in Recurrent "proximal-type" epithelioid sarcoma of the vulva (n=1). Fine-needle aspiration cytology was evaluated on Cytologic and immunocytologic findings. Fine-needle aspiration cytology of proximal-type epithelioid sarcoma showed large, atypical neoplastic cells with rhabdoid-like morphology, correlating well with histopathology.
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