Key result
Next-generation sequencing of viral isolates from 184 military trainees with respiratory infections identified HAdV4 (77 isolates) and coxsackievirus A21 (17 isolates) as significant pathogens.
Why the study?
What are the viral etiologies of respiratory infections among unvaccinated US Army Basic Trainees?
Population
184 United States Army Basic Trainees with respiratory infections at Fort Jackson, South Carolina in 2002
Design
Cohort
Authors
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HAdV4 predominance supports enhanced surveillance in unvaccinated trainees; leaves open CAV21's role requiring further study.
Observational (n=184)
No
What are the viral etiologies of respiratory infections among unvaccinated US Army Basic Trainees?
HAdV4 is the predominant respiratory pathogen in unvaccinated military trainees, while CAV21 is also a significant pathogen requiring further evaluation.
Hang et al. (2017) conducted an observational in Acute respiratory disease (n=184). Viral etiology investigation using next-generation sequencing was evaluated on Identification of viral genotypes. Next-generation sequencing of viral isolates from 184 military trainees with respiratory infections identified HAdV4 (77 isolates) and coxsackievirus A21 (17 isolates) as significant pathogens.
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