Harnessing genetic diversity and the introduction of elite alleles from wild relatives or landraces into commercial cultivars has been a major goal in crop breeding programs. Precise modification of the plant genome through clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) (CRISPR/Cas)-mediated homology-directed repair (HDR) offers a great promise to introduce elite alleles from wild relatives or landraces into commercialized cultivars in the short term.
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Li et al. (2020) studied this question.
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