Contemporary Prosthetic Joint Infection Management: Is There a Role for Suppressive Antibiotic Therapy?

Deep infection after hip and knee replacement surgery remains one of the major challenges facing orthopedic surgeons in the 21st century. Infection is responsible for 14.8% of revision total hip arthroplasty procedures and 25.2% of all revision knee arthroplasty procedures [1]. Infection also remains a major cause of re-revision [2]. As the population ages, the number of comorbidities increase, and the number of total hip and knee procedures increase, the number of cases of prosthetic joint infection (PJI) are likely to increase [3].