The extraction equilibrium of organic acids (acetic, glycolic, propionic, lactic, pyruvic, butyric, succinic, fumaric, maleic, malic, itaconic, tartaric, citric and isocitric) with tri-n-octylphosphine oxide (TOPO) was measured. The solvation numbers of the acids were the same as the numbers of the carboxyl groups on each acid molecule. The extraction equilibrium constant was controlled by the hydrophobicity of the acid when hexane was used as a diluent.
No takes yet. Share an insight, caveat, or question.
Hano et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: