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Apart from the risk of increasing the concentration of HIV infection in genital secretions, consequences of sexually transmitted infections (STI) can be grave, resulting in conditions such as infertility, ectopic pregnancy, cancer and neonatal infections. Urogenital tract swab samples including urethral swabs (URS), endocervical swabs (ECS) and high vaginal swabs (HVS) were aseptically collected from 158 HIV positive individuals presented with symptoms of urogenital tract infections at federal medical centre, Gombe between May to September, 2009. These were subjected to microscopy, culture and sensitivity testing (using AbtecAE sensitivity discs). Out of the samples, 30 (18.9%) produced bacterial growth. In the male category, highest percentage of bacteria isolated was in the age group 11-20yrs (20.0%), while in the female category, it was in the age group 41-50yrs (25.0%). No bacteria isolated at age e51yrs in both sexes. Six opportunistic bacterial species were isolated of which Staphylococcus aureus had the highest frequency of 9 (30.0%) while Enterococcus faecalis had the lowest as 1(3.3%). The most active drug against S. aureus observed was augmentin (71.4%). Two exogenous bacterial species were also isolated; Neisseria gonorrhea which was resistant to tetracycline and Haemophilus species which was sensitive to all but cotrimotazole and fusidin. This work recommended the need for the hospitals to improve in partner notification and treatment, early and correct diagnosis to the patients and use of augmentin, gentimicin and sparfloxacin in symptomatic treatment, where laboratory investigations are not available.
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