Why the study?
Does succinylcholine administration cause hyperkalemia in massively traumatized patients?
Does succinylcholine administration cause hyperkalemia in massively traumatized patients?
Administration of succinylcholine to massively traumatized patients is associated with a severe increase in arterial potassium, which can lead to cardiovascular collapse.
Succinylcholine was associated with severe hyperkalemia in massively traumatized patients; leaves open whether randomized data are needed before practice change.
Mean arterial potassium increased 84 per cent in 14 massively traumatized soldiers following administration of succinylcholine, 1 mg/kg, for intubation. A control group of patients showed only an 11 per cent increase. In five traumatized patients, potassium increased from an average of 3.8 mEg/1 lo
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Mazze et al. (1969) studied this question.
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