TerpyRu(PPh 3 )Cl 2 is an efficient catalyst for rearranging aldoximes to amides without the need for chelating phosphines or additives as in prior examples. The catalyst is also useful in converting aldehydes into amides in a one-pot process using NaHCO 3 as an additive. A mechanism involving nucleophilic attack of deprotonated oxime on an adjacent nitrile is suggested.
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Gnanamgari et al. (2009) studied this question.
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