Adapt to react: METAMORPhos ligands are a class of flexible and adaptive hydrogen-bonded multidentate sulfonamide-based phosphorus ligands. Selective formation of complexes with two different METAMORPhos ligands (see scheme) that display unusual kinetic behavior leads to the proposal of a new mechanism. These complexes are highly reactive and enantioselective in the rhodium-catalyzed asymmetric hydrogenation of alkenes.
No takes yet. Share an insight, caveat, or question.
Patureau et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: