A biodegradable microfabrication platform for constructing 3D high- resolution devices for tissue engineering and drug delivery is presented. Biodegradable polymer films with built-in micrometer-scale features are stacked and fusion bonded to construct fully biodegradable, poly(DL-lactic-co-glycolide) (PLGA)-based, monolithic, multilayer, microfluidic networks. Integration with cells or drug compounds will enable use of these devices in therapeutic applications (scale bar: ∼ 300 μm).
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King et al. (2004) studied this question.
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