July 1, 1998The Journal of Clinical Endocrinology & Metabolism

Compound Heterozygous Deletion of the PROP-1 Gene in Children with Combined Pituitary Hormone Deficiency

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Population

14 children with combined pituitary hormone deficiency (CPHD) from Russian families

Design

Case_series

Authors

QFQ. Fofanova

Discussion

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Implication

Provides initial evidence for PROP1 deletions in Russian CPHD; leaves open diagnostic utility pending larger confirmatory studies.

Structured PICO

Population

14 children with combined pituitary hormone deficiency (CPHD) from Russian families

Outcome

Detection of compound heterozygosity for PROP1 mutations

This study provides the first evidence of compound heterozygosity for two common PROP1 deletions as a cause of combined pituitary hormone deficiency in Russian children.

Cite This Study

Q. Fofanova (1998) studied this question.

synapsesocial.com/papers/6a952af92273404a50fa5fb0 https://doi.org/10.1210/jc.83.7.2601

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Compound Heterozygous Deletion of the PROP-1 Gene in Children with Combined Pituitary Hormone Deficiency

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Compound Heterozygous Deletion of the PROP-1 Gene in Children with Combined Pituitary Hormone Deficiency

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider