Why the study?
The association between maternal body mass index at delivery, skin incision-to-delivery time, and umbilical artery pH <7.0 was not well defined.
Is higher maternal BMI associated with longer skin incision-to-delivery time and increased risk of umbilical artery pH <7.0 in cesarean deliveries?
Is higher maternal BMI associated with longer skin incision-to-delivery time and increased risk of umbilical artery pH <7.0 in cesarean deliveries?
In cesarean deliveries, severe maternal obesity (BMI ≥50 kg/m2) is associated with prolonged skin incision-to-delivery times and an increased risk of fetal acidemia (umbilical artery pH <7.0).
Maternal BMI ≥50 kg/m² was associated with longer incision-to-delivery intervals and UA pH <7.0; leaves open whether expediting delivery reduces acidosis risk in severe obesity.
Objective To estimate the association between maternal body mass index (BMI) at delivery, time from skin incision to infant delivery, and umbilical artery (UA) pH <7.0. Methods This was a secondary analysis of the Assessment of Perinatal Excellence, a multicenter observational study of an obstetrical cohort of individuals who delivered between 2008 and 2011 in the United States. This analysis included women who delivered via cesarean with known BMI at delivery, skin incision-to-delivery time, and UA pH. Multivariable linear regression assessed the association between BMI and time from skin incision to infant delivery while multivariable logistic regression estimated the associations of BMI and time from skin incision to delivery with UA pH <7.0. An interaction between BMI and skin incision-to-delivery time was evaluated to examine their combined effect on UA pH <7.0. Results A total of 16,723 women were included across five BMI groups. Increasing BMI was associated with longer time intervals from skin incision to delivery and higher rates of UA pH <7.0. After controlling for potentially confounding factors, all BMI groups ≥25 kg/m 2 were associated with longer time intervals from skin incision to delivery. Specifically, BMI groups of 40-49.9 kg/m 2 and ≥50 kg/m 2 had skin incision-to-delivery times that were 1.30 (95% CI 1.23-1.36) and 1.44 (95% CI 1.34-1.55) times longer, respectively, compared with BMI <25 kg/m 2 . In the multivariable logistic regression, BMI group ≥50 kg/m 2 remained associated with higher odds of UA pH <7.0. There was a significant interaction between BMI and time from skin incision to delivery regarding the risk of UA pH <7.0 (p for the interaction term=.003). Conclusion Maternal BMI ≥50 kg/m 2 was associated with longer time from skin incision to infant delivery and higher odds of UA pH <7.0. Skin incision-to-delivery time had a differential impact on UA pH in each BMI group. Precis In cesarean deliveries, maternal body mass index ≥50 kg/m 2 and prolonged skin incision-to-delivery time increase the risk of umbilical artery pH <7.0.
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Sunji et al. (2025) studied this question.
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