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This research aims to identify perinatal factors related to umbilical arterial pH in neonates born by cesarean section.

Factors associated with umbilical arterial blood pH in term neonates delivered via cesarean section: A retrospective cohort study

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Retrospective cohort study shows cesarean section influences neonatal pH and risk stratification for acidosis.

This research aims to identify perinatal factors related to umbilical arterial pH in neonates born by cesarean section.
Analyzed clinical data from 356 mother-neonate pairs who underwent cesarean delivery.
Neonates were categorized based on umbilical arterial pH values (<7.20 vs. ≥7.20).
Evaluated maternal factors including amniotic fluid quality and fetal distress.
Used multivariable logistic regression and random forest modeling for statistical analyses.
51.0% of neonates had acidosis (umbilical arterial pH <7.20).
Meconium-stained amniotic fluid significantly increased acidosis risk (adjusted odds ratio: 3.12).
Trial of labor also increased risk of acidosis (adjusted odds ratio: 2.45).
Random forest model revealed top predictors with an area under the curve of 0.71.

Linlin et al. (2025) studied this question.

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