Local Inflammatory Diseases Are at Risk of Developing Myocardial Infarction, Stroke, Renal Failure and Cancer via Chronic Systemic Inflammation

Inflammatory diseases at various anatomic sites, regardless how mild it appears, should not be taken lightly. If not treated, the chronic inflammation associated with the local inflammatory disease can lead to further development of fatal diseases such as myocardial infarction (MI), stroke, renal failure, cancer and even chronic obstructive pulmonary disease. Inflammatory mediators generated from the local inflammation reaction will spread systemically and attack on cells of other organs and tissues. More than one target of cells may be attacked at the same time leading to the onset of new, multiple inflammatory diseases. Because inflammation is also known to play an important role in the pathogenesis and diseases progression of all fatal degenerative diseases, it is conceivable why patients with mild local inflammatory diseases are at risk of developing MI, stroke, renal failure and cancer.