Answers are grounded in this paper and cite their sources.
β-Ketoesters and β-diketones are α-hydroxylated by molecular oxygen in the presence of 5 mol% CeCl3·7 H2O in i-PrOH as solvent. The method is limited to substrates with an α-alkyl substituent. Optimal yields are achieved with cyclic starting materials.
No takes yet. Share an insight, caveat, or question.
Christoffers et al. (2002) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: