Why the study?
Does impaired fasting glucose or Type 2 Diabetes Mellitus influence coronary risk estimated by the Framingham-Wilson equation compared to normal fasting glucose in adult subjects?
Does impaired fasting glucose or Type 2 Diabetes Mellitus influence coronary risk estimated by the Framingham-Wilson equation compared to normal fasting glucose in adult subjects?
This study aims to evaluate the estimated coronary risk associated with impaired fasting glucose using a recalibrated Framingham-Wilson equation in a Venezuelan population.
Coronary risk estimation with impaired fasting glucose needs local validation; leaves open Framingham-Wilson applicability in Venezuelan adults.
Introduction: Type 2 Diabetes Mellitus (T2DM) is an independent risk factor for coronary artery disease. Nevertheless, the coronary risk rendered by pre-diabetes states such as Impaired Fasting Glucose (IFG) has not been thoroughly explored. The purpose of this study was to evaluate the influence of glycemic status on coronary risk estimated by the recalibrated Framingham-Wilson equation in our population. and Methods: A total 1,378 of subjects were selected from the Maracaibo City Metabolic Syndrome Prevalence Study. A complete medical history was taken, next to laboratory workup and anthropometric measurement. All subjects were classified according to glycemic status in normal fasting glucose (NG), impaired fasting glucose (IFG), and T2DM. Coronary risk estimation was calculated using the Framingham-Wilson equation recalibrated for our population.
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Valmore et al. (2014) studied this question.
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