Why the study?
What are the etiologies of hospital-acquired hyponatremia and does it affect morbidity and mortality in PICU patients?
What are the etiologies of hospital-acquired hyponatremia and does it affect morbidity and mortality in PICU patients?
Hospital-acquired hyponatremia in the PICU is driven by increased fluid intake, ADH-stimulating conditions, and postsurgical status, and is associated with increased morbidity but not mortality.
May warrant vigilance for morbidity in PICU hyponatremia without changing practice; leaves open causal effects and intervention trials.
OBJECTIVE: The objective of the study was to evaluate the etiology of hospital-acquired hyponatremia (HAH) and its effects on morbidity and mortality in the Pediatric Intensive Care Unit (PICU) patients. DESIGN: This study design was a prospective observational case-control study. SETTING: this study was conducted at tertiary care PICU. MATERIALS AND METHODS: < 35 mEq/L) 7 days or PICU discharge whichever was earlier. RESULTS: = 0.01), but no difference in the mortality when compared to controls. CONCLUSIONS: HAH is associated with increased fluid intake, presence of ADH-stimulating drugs or conditions, and postsurgical status and has an adverse effect on the outcome of PICU patients.
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Pandharikar et al. (2017) studied this question.
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