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August 31, 2026Frontiers in NeurologyOpen Access

Effects of music-based interventions on rehabilitation outcomes after stroke: a systematic review and meta-analysis of randomized controlled trials

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Authors

DLDelin LiuTKTengteng KangLYLiang Yakun

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Overview

Systematic review and meta-analysis reveals improved motor and functional outcomes in stroke patients, indicating music is an effective rehabilitation adjunct.

Key Points

  • To systematically evaluate the impact of music-based interventions on rehabilitation outcomes in patients recovering from stroke.
  • Searched 11 electronic databases from inception through April 7, 2026, for randomized controlled trials comparing music-based interventions plus conventional rehabilitation against conventional rehabilitation alone.
  • Identified and analyzed 21 randomized controlled trials involving a total of 1,029 patients with stroke using Review Manager (RevMan) 5.4.
  • Music-based interventions significantly improved lower limb motor function [SMD = 0.99, 95% CI (0.59, 1.39), p < 0.001], upper limb motor function [SMD = 0.58, 95% CI (0.26, 0.91), p = 0.0004], and balance [SMD = 0.45, 95% CI (0.17, 0.74), p = 0.002].
  • Interventions produced significant enhancements in gait speed [SMD = 0.89, 95% CI (0.16, 1.62), p = 0.02], activities of daily living [SMD = 0.88, 95% CI (0.68, 1.08), p < 0.001], and quality of life [SMD = 0.31, 95% CI (0.13, 0.49), p = 0.0009].

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a9541eaf20e493292a741a7https://doi.org/10.3389/fneur.2026.1907080
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