What question did this study set out to answer?

To examine variations in circulating lipids, glucose, and ketone bodies across pregnancy, lactation stages, and sire progeny groups in dairy cattle to assess genetic predisposition to acetonaemia.

May 13, 2010Zentralblatt für Veterinärmedizin Reihe A

“Lipid Pattern”, Glucose Concentration, and Ketone Body Level in the Blood of Cattle: Variations with age, stage of lactation, and between groups of half-sisters*

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Authors

BHB. HenricsonRoyal Veterinary College GJGöran JönssonLund University BPB. PehrsonSwedish Veterinary Agency

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Implication

Longitudinal study reveals metabolic shifts and sire-group variations in dairy cattle, suggesting a genetic predisposition to acetonaemia.

Key Points

To examine variations in circulating lipids, glucose, and ketone bodies across pregnancy, lactation stages, and sire progeny groups in dairy cattle to assess genetic predisposition to acetonaemia.
Obtained longitudinal blood samples from 35–40 daughters from each of 20 Swedish Red and White bulls (N ≈ 700–800 cows).
Sampled cattle across five physiological timepoints: early first pregnancy, early second pregnancy, and 25–30 days after the first, second, and third calvings.
Quantified concentrations of phospholipids, cholesterol, triglycerides, acetate, non-esterified fatty acids (NEFA), glycerol, and glucose, analyzing differences by lactation stage and sire group.
Phospholipid and cholesterol concentrations were higher in lactating than non-lactating cows, whereas triglycerides were substantially higher in non-lactating cows and showed a weak negative correlation with milk yield.
NEFA and glycerol levels indicated elevated body fat mobilization during the first 6–8 weeks post-calving, while blood glucose one month postpartum decreased progressively from the first to the third lactation alongside increasing acetonaemia incidence.
Significant differences in blood glucose and acetonaemia incidence were observed between bull daughter-groups, demonstrating a genetic predisposition to acetonaemia, although individual lipid and glucose metrics could not predict disease susceptibility.

Cite This Study

Henricson et al. (2010) studied this question.

synapsesocial.com/papers/6a9543870cf8d0f2c97cf8ae https://doi.org/10.1111/j.1439-0442.1977.tb01555.x

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Implication

Longitudinal study reveals metabolic shifts and sire-group variations in dairy cattle, suggesting a genetic predisposition to acetonaemia.

“Lipid Pattern”, Glucose Concentration, and Ketone Body Level in the Blood of Cattle: Variations with age, stage of lactation, and between groups of half-sisters*

Discussion

Member takes

Implication

Key Points

Cite This Study

“Lipid Pattern”, Glucose Concentration, and Ketone Body Level in the Blood of Cattle: Variations with age, stage of lactation, and between groups of half-sisters*

Discussion

Member takes

Implication

Key Points

Cite This Study

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