Primary cardiac lymphoma is an extremely rare diagnosis that can present as a left atrial mass mimicking a myxoma and causing mitral regurgitation.
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Left atrial masses may represent primary cardiac B-cell lymphoma; this case extends the differential but leaves management questions open.
Primary cardiac lymphoma (PCL) is an extremely rare diagnosis. We present a case of a 38-year-old immunocompetent female who presented with dyspnea on exertion and chest pain and the echocardiography revealed a mass in the left atrium (LA) causing moderate mitral regurgitation and mimicking a left atrial myxoma. The patient was managed with excision of the mass and mitral valve replacement followed by chemotherapy. The histopathology revealed B-cell non-Hodgkin lymphoma (NHL) with tumor cells showing immunoreactivity with CD20 and negative for CD45RO.
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Sharma et al. (2012) studied this question.
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