Key result
Elevated serum procalcitonin levels were independently associated with in-stent restenosis in patients undergoing bare-metal stent implantation.
Why the study?
Is pre-procedural serum procalcitonin level an independent predictor of in-stent restenosis in patients undergoing bare-metal stent implantation?
Case-Control (n=240)
Is pre-procedural serum procalcitonin level an independent predictor of in-stent restenosis in patients undergoing bare-metal stent implantation?
Elevated pre-procedural serum procalcitonin levels are independently associated with an increased risk of in-stent restenosis after bare-metal stent implantation.
Answers are grounded in this paper and cite their sources.
May support procalcitonin as a restenosis marker; hypothesis-generating and should not yet change BMS practice.
AIM: Procalcitonin (PCT) is an inflammatory marker and elevated PCT levels are associated with cardiovascular events. We assessed whether PCT level is an independent predictor of bare-metal stent (BMS) in-stent restenosis (ISR). PATIENTS & METHODS: We evaluated 240 patients undergoing BMS implantation. Serum PCT levels were measured before procedure. Patients were classified as ISR(-) group (n = 120) and ISR(+) group (n = 120). RESULTS: Serum PCT levels were higher in the ISR (+) group (p < 0.001). At multivariate analysis, PCT (odds ratio [OR] 1.561; p = 0.012), stent length (OR: 1.089), stent diameter (OR: 0.141) and uric acid (OR: 1.465) were independent predictors of ISR. CONCLUSION: Serum PCT is independently associated with ISR and increased PCT levels may provide useful information for the risk of BMS-ISR.
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Örnek et al. (2018) conducted a case-control in Bare-metal stent implantation (n=240). Serum procalcitonin (PCT) level vs. Lower serum procalcitonin levels was evaluated on In-stent restenosis (ISR) (OR 1.561, p=0.012). Elevated serum procalcitonin levels were independently associated with in-stent restenosis in patients undergoing bare-metal stent implantation.
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