Key result
Late-systolic mitral valve prolapse was associated with significantly greater systolic mitral valve annular expansion (1.6 vs 0.1 cm2/m2) compared to holo-systolic prolapse.
Why the study?
The mechanism underlying systolic annular expansion in mitral valve prolapse has not been clarified.
Observational (n=70)
Systolic mitral valve annular expansion in late-systolic mitral valve prolapse is independently associated with abnormal mitral valve leaflet lengthening and papillary muscle superior shift.
May refine MVP annular dynamics understanding; hypothesis-generating, requires prospective validation before practice impact.
The mechanism of systolic annular expansion in mitral valve prolapse (MVP) is not clarified. Since annular expansion is systolic outward shift of MV leaflet/chorda tissue complex at superior and outer ends, annular expansion could be related to inward (superior) shift of the complex at another inferior and inner end of the papillary muscle (PM) tip and/or systolic lengthening of the tissue complex, especially MV leaflets.
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Hei et al. (2020) conducted an observational in Mitral valve prolapse (n=70). Late-systolic mitral valve prolapse vs. Holo-systolic mitral valve prolapse was evaluated on Systolic mitral valve annular expansion (ΔMV annulus area in cm2/m2) (p=<0.001). Late-systolic mitral valve prolapse was associated with significantly greater systolic mitral valve annular expansion (1.6 vs 0.1 cm2/m2) compared to holo-systolic prolapse.
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