Why the study?
Does mitral valve prolapse alter the size and motion of the mitral valve annulus compared to normal subjects?
Population
17 patients with mitral valve prolapse (MVP) and 12 normal subjects
Comparison
Two-dimensional echocardiography vs Normal subjects
Design
Cross-sectional
Authors
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Annular dilatation with reduced contraction in MVP-MR supports further mechanistic study; leaves open causality and intervention targets.
Does mitral valve prolapse alter the size and motion of the mitral valve annulus compared to normal subjects?
Mitral valve prolapse is associated with primary mitral annular dilatation and abnormal systolic annular area reduction, particularly in patients with significant mitral regurgitation.
Ormiston et al. (1982) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: