Key result
SiPUU with PHMO-MDI-PHMO and PHMO-IPDI-PHMO linked macrodiols showed enhanced creep resistance, recovery, tensile stress, and tear strengths compared with a commercial biostable polyurethane.
Population
Siloxane poly(urethane-urea) (SiPUU) materials developed for heart valve application
Comparison
Incorporation of a macrodiol linked with a… vs Commercial biostable polyurethane, Elast-Eon™ 2A
Design
Preclinical
Authors
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Supports preclinical heart valve material development; leaves open durability and safety in clinical translation.
The incorporation of linked macrodiols into siloxane poly(urethane-urea)s improves their mechanical properties and creep resistance, making them promising biomaterials for heart valve applications.
Dandeniyage et al. (2018) studied Heart valve application (materials). Siloxane poly(urethane-urea) (SiPUU) with linked macrodiols vs. Commercial biostable polyurethane, Elast-Eon™ 2A was evaluated on Morphology, surface properties, surface elemental composition, and creep resistance. SiPUU with PHMO-MDI-PHMO and PHMO-IPDI-PHMO linked macrodiols showed enhanced creep resistance, recovery, tensile stress, and tear strengths compared with a commercial biostable polyurethane.
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