Key result
Pacemaker explantation and systemic amphotericin B therapy successfully treated a Candida albicans pacemaker site infection in a diabetic man, with no recurrence at 2 years.
Case Report (n=1)
This case highlights the susceptibility of diabetic patients to rare fungal pacemaker site infections like Candida albicans and demonstrates successful management with explantation, amphotericin B, and contralateral reimplantation.
A 69-year-old man with a history of diabetes and episodic lymphocytopenia underwent pacemaker implantation for complete heart block. Despite prophylactic antibiotics, pocket irrigation, and strict sterile technique, a fungal (Candida albicans) pacemaker site infection developed that required pacemaker explanation and systemic amphotericin B therapy. After 3 days of temporary pacing, a second pulse generator was implanted on the opposite side. At 2-year follow-up, he has had no recurrence of pacemaker infection. This report underscores the predilection of diabetics for infections, and in particular, their susceptibility to Candida albicans.
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Cohen et al. (1991) conducted a case report in Candida albicans pacemaker site infection (n=1). Pacemaker explantation and systemic amphotericin B therapy was evaluated on Recurrence of pacemaker infection. Pacemaker explantation and systemic amphotericin B therapy successfully treated a Candida albicans pacemaker site infection in a diabetic man, with no recurrence at 2 years.
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