Population
Sendai virus-infected BHK cells and preinitiated intracellular Sendai virus defective interfering particle…
Comparison
Purified Sendai virus major nucleocapsid protein vs Absence of NP protein or soluble protein…
Design
Preclinical
Authors
Loading...
NP sufficiency for post-initiation synthesis informs antiviral models; leaves open additional factors required for virion-initiated replication.
The Sendai virus NP protein is necessary and sufficient for in vitro genome RNA synthesis and encapsidation from preinitiated templates, but an additional viral component is required for initiation from purified virions.
Baker et al. (1988) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: