Key result
Post-operative bed rest following aortocoronary bypass surgery significantly increased calf vein compliance by 48% at 7 days compared to pre-operative baseline (0.065 vs 0.044; P<0.001).
Why the study?
Does post-operative bed rest after aortocoronary bypass surgery alter calf vein compliance?
Observational (n=50)
Does post-operative bed rest after aortocoronary bypass surgery alter calf vein compliance?
Calf vein compliance increases significantly following bed rest after aortocoronary bypass surgery, which may have implications for the prophylactic management of venous thrombosis and orthostatic hypotension.
Early post-operative ambulation (< 3 days) is expected to decrease the risk of venous thrombosis, whereas late ambulation (> 7 days) increases the risk of orthostatic hypotension. The effect of post-operative bed rest on calf vein compliance was studied before (D - 1) and 7 days (D + 7) after aortocoronary bypass surgery in 50 patients (41 men and nine women, 65 +/- SD 10 years). Calf vein compliance was measured by strain gauge plethysmography and stepwise increases in thigh congestive pressure from 20 to 60 mmHg. Calf compliance [median (25 percentile-75 percentile)] increased significantly by 48% from D - 1 to D + 7 [0.044 (0.039-0.051) vs. 0.065 (0.048-0.083) ml (100 ml mmHg)-1, P < 0.001]. This increase was reflected as increased calf volume for the 50 mmHg [D-1 2.10 (1.75-2.65) vs. D + 7 2.60 (1.70-3.00) ml 100 ml-1, P < 0.01] and 60 mmHg [D - 1 2.50 (2.10-2.95) vs. D + 7 3.20 (2.30-4.00) ml 100 ml-1, P < 0.001] occlusion pressure levels. The associated pathologies (diabetes and arterial hypertension) and NYHA grades had no significant influence on the increase in compliance. Among the vasoactive therapeutic regimens, calcium channel blockers contributed significantly to the increased calf compliance, but only on D-1. The increase in venous compliance following aortocoronary bypass surgery is multifactorial but should be considered for prophylactic management of these patients.
No takes yet. Share an insight, caveat, or question.
Lefthériotis et al. (1998) conducted an observational in aortocoronary bypass surgery (n=50). Post-operative bed rest vs. Pre-operative baseline (D - 1) was evaluated on Calf vein compliance (p=< 0.001). Post-operative bed rest following aortocoronary bypass surgery significantly increased calf vein compliance by 48% at 7 days compared to pre-operative baseline (0.065 vs 0.044; P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: