Cushing's Syndrome and Pregnancy

Summary: The literature on Cushing's syndrome associated with pregnancy is reviewed, and the first case to be reported of pituitary‐dependent adrenal hyper‐plasia treated by pituitary irradiation during pregnancy is described. Vaginal delivery at term resulted in a normal female infant. The interpretation of plasma cortisol levels after pituitary irradiation is discussed and, in particular, the effect of the latter on diurnal variation of cortisol levels and dexamethasone suppression.